Previous studies showed that ACTC1 is related to cancer prognosis (72, 73), ACTC1 expression is significantly upregulated in glioblastoma and inhibits migration of cancer cells (74), and ACTC1 correlates with the prognosis of glioblastoma and can be used as a novel prognostic marker in glioma (72). The gene discussed is ACTC1; the disease is cancer.