AKT1 and cancer: LMP-1 is one of the oncoproteins of the EBV virus and can stimulate various carcinogenic pathways and acts as a TNF receptor in several signaling pathways, including NF-B1 and ERK-MAPK, NF-kB2, PI3K/Akt, p38-MAPK, JNK/SAPK, and TGF- which are regulated in various cancers.