Third, we observed decreased EGFR in HF-fed Maf1hep−/− mice, which may seem surprising as EGFR promotes cell proliferation, and liver weights of HF-fed Maf1hep−/− seemed to increase in the refed state, albeit the Bonferroni-corrected p-value was above our threshold (Supplementary Table S1). This evidence concerns the gene EGFR and hydrops fetalis.