It is worth noting that GH is implicated in liver lipogenesis and hepatosteatosis (Takahashi, 2017): changes in GH secretion might thus be at least partially responsible for the increased hepatosteatosis phenotype observed in the HF-fed Maf1hep−/− mice (Barclay et al., 2011; Le Magueresse-Battistoni, 2021). The gene discussed is GH1; the disease is hydrops fetalis.