ANG and neoplasm: Angiogenin owes its name to its promoting angiogenesis during tumor growth but has numerous other functions such as i) promoting the production of the large ribosomal RNAs (Pizzo et al., 2013; Lyons et al., 2017), ii) cleaving tRNAs under stress conditions thus generating tRNA halves that can inhibit translation and promote survival through inhibition of apoptosis (Sheng and Xu, 2016), and iii) other ill-defined activities (Lyons et al., 2017; Rashad et al., 2020).