Strikingly, the Chow or HF-fed Maf1hep−/− cohorts revealed no changing RNAs except for Maf1 and Gm35339 (Figure 3 and Supplementary Table S5), the locus downstream of Maf1 whose predicted WD40 repeat protein was undetectable (see below) and whose RNA upregulation does not seem to contribute to the Maf1−/− mouse phenotype (Bonhoure et al., 2015). The gene discussed is MAF1; the disease is hydrops fetalis.