HDV infection did not significantly change the cell surface expression of the NK cell ligands MICA/B, NKp30/44 ligands, CD54, CD112, OX40L, HVEM, B7H6 and PD-L1 or the expression of HLA molecules on infected hepatoma cells (Figure 1B). The gene discussed is TNFSF4; the disease is hepatocellular carcinoma.