The patient was a 25-year-old male with paranoid schizophrenia who had successful treatment with olanzapine (10 mg/day). The patient received a first-episode psychosis MRI, which revealed a pituitary macroadenoma measuring 1.6 cm in size and a prolactin level of 1986.5 ng/ml. The patient was subsequently operated on, and prolactin levels fell. The patient was put on long-acting risperidone (dosage unspecified) and has been psychologically well since, with a small increase in overall prolactin levels. The gene discussed is PRL; the disease is psychotic disorder.