Thus, the high levels of ICAM‐1+EV observed in the blood of COVID‐19 patients may directly contribute to immune thrombosis.[195] PS is often linked to thrombo‐inflammation in COVID‐19, and circulating EVs in COVID‐19 patients induce an increase in PS‐dependent neutrophil adhesion.[179] Peripheral blood mononuclear cells (PBMC) from COVID‐19 patients exhibited high surface exposure to PS, which correlates with the presence of PS+EVs and the severity of the disease. Here, ICAM1 is linked to COVID-19.