Studies have shown that the products of CCL25 bind to the chemokine receptor CCR9 and promote cytokine-induced apoptosis by inhibiting insulin secretion, thereby impacting pancreatic β-cell function (Atanes et al. 2020), which may be a way that CCL25 protein plays a role in the development of T1D. The gene discussed is INS; the disease is type 1 diabetes mellitus.