Table 1, Table S1 and Figure S1 show cohort demographics, comorbidities and disease characteristics. Spike and nucleocapsid proteins have previously been detectable in COVID-19 PMLT analysed by IMC15. However, using single cell expression data in positive and negative infected cultured cells as controls, we did not detect spike or nucleocapsid protein in any of the pathology phenotypes (Figure S3). This could be related to insufficient sensitivity of IMC analysis or support a ‘hit and run’ hypothesis whereby immunopathology is topically dissociated from virus.2 Here, CHMP5 is linked to COVID-19.