CD68 and obesity due to melanocortin 4 receptor deficiency: In contrast, it did stain some CD68-positive macrophages forming CLSs (Figure 5D and G-I) or MGCs (Figure 5E and G-I) as well as some interstitial macrophages found among adipocytes (Figure 5F and J-L) in 16 of the 31 subjects with obesity, albeit with considerable variability in the degree of positivity.