CHAT and obesity due to melanocortin 4 receptor deficiency: Morphometric analysis of omental fat samples containing ChAT-positive cells from 7 obese subjects disclosed that only 64.68% ± 2.37 of ChAT-positive interstitial cells were also positive for the CD68 macrophage marker, suggesting that also in humans other infiltrating cells besides macrophages acquire the ability to synthesize ACh in obesity conditions.