Youth with TPD had higher CRP (Hedge’s g = 0.38, 95%CI0.05 – 0.70, k = 3, N = 219, I2 = 28%) compared to youth without psychosis (Ceylan et al., 2023; Chen et al., 2021; Wedervang-Resell et al., 2020). Here, CRP is linked to psychotic disorder.