Among these are the correlations regarding proinflammatory cytokines IL-6 and TNF-α with the immunosuppressive cytokine IL-10 for a poor prognosis of EOC, the correlation between elevated levels of IFN-γ and increased survival, and the correlation between elevated levels of IL-6 and IL-10 with lower survival rates.21However, the complex network of interactions involving these structures has not been clearly elucidated, and a better understanding may lead to the development of potential cancer therapies. This evidence concerns the gene TNF and cancer.