But a combination of serum decorin with CL measurements predicted preterm delivery before 37 weeks.43In the study by Underhill and et al., patients with PPROM had high serum biglycan levels and low decorin levels.38In the present study, in the univariate analysis, similar to Underhill et al., decorin and biglycan were found to be significant in predicting preterm delivery. The gene discussed is DCN; the disease is preterm premature rupture of the membranes.