Consistent with our observation of decreased glycolysis in response to PFD treatment in NSCLC cells, PFD increased the protein expression of the epithelial marker E cadherin to inhibit EMT (Figure 4A,B), especially in lymph node‐metastatic lung adenocarcinoma H1299 cells, which have a highly glycolytic phenotype. This evidence concerns the gene CDH1 and non-small cell lung carcinoma.