Interestingly, the protein expression of glycolysis‐related enzymes (HK2, PKM2, LDHA and GLUT1) in the PFD‐pretreated group was not decreased compared with that in the control group, as determined by western blotting (Figure 7A), probably because PFD alters the expression of key glycolytic enzymes in a time‐dependent manner. The gene discussed is LDHA; the disease is polyostotic fibrous dysplasia.