In a study conducted by Kuang,288 it was discovered that indirubin stimulates lipid peroxidation in breast cancer cells, resulting in reduced glutathione (GSH) levels, increased malondialdehyde (MDA) and 4‐Hydroxynonenal (4‐HNE) levels and decreased glutathione peroxidase 4 (GPX4) expression. The gene discussed is GPX4; the disease is breast cancer.