,32,33 To determine whether sustained IL-7Rα expression on dex-CAR T cells conferred improved biological activity, we treated ALL-bearing mice with dex-CAR (Figure 5A) in combination with exogenous IL-7 administered through i.p. injections of human (hu)IL-7-secreting CHO cells. The gene discussed is IL7R; the disease is acute lymphoblastic leukemia.