LGALS1 and neoplasm: Moreover, the abnormal expression of Syn-1 was reported in several tumor cells and linked to the fusion between cancer and endothelial cells [46,47,49,50], a process that could also involve Gal-1, as the expression and secretion of this galectin is induced in the endothelial cells that surround tumors to stimulate tumoral angiogenesis [94,102].