Changes in lipid droplet-associated proteins, such as perilipins, adipose differentiation-related protein (ADRP), and seipin, induced by ER stress, can potentially impact lipid droplet formation, growth, and turnover, which, in turn, can alter cellular lipid storage capacity, lipolysis, and lipid utilization [276,277,278]. The gene discussed is PLIN1; the disease is psychosocial stress measurement.