All of the studies were designed to be eucaloric and found a low-CHO diet to lower fasting insulin [72,73,74], glucose [73], total cholesterol [72,73], LDL-C concentrations [73,74], HOMA-IR [73], and area under the curve insulin [74], as well as to improve insulin sensitivity [73] in individuals with PCOS. Here, INS is linked to polycystic ovary syndrome.