Afrin R. et al. further analyzed the effects of curcumin on the progression of MASH in a mouse model of HCC and found that the biological compound was able to attenuate oxidative stress by decreasing the hepatic expression of cytochrome P450 family 2 subfamily E member 1 (CYP2E1) and CCAAT/enhancer binding proteins (C/EBPβ) [42]. Here, CYP2E1 is linked to hepatocellular carcinoma.