The disease can have either an early onset (EOMG) or late-onset MG (LOMG) and can be further subcategorized by the type of antibodies the patient presents, including auto-antibodies against the acetylcholine receptor (AChR), muscle-specific kinase (MuSK), lipoprotein related protein 4 (LRP4), agrin and rapsyn [2,3,4,5,6]. The gene discussed is LRP4; the disease is myasthenia gravis.