Thus, to validate and confirm the immunological importance of the mutated epitopes of the new variants, six IgA–epitope peptides (#SC/13huA to #SC/18huA) were synthesized covalently attached on cellulose support (SPOT synthesis) as described before and evaluated using a pool (n = 10; Table S3) of sera from the hospitalized patient who had been independently confirmed with COVID-19 by PCR. The gene discussed is CD79A; the disease is COVID-19.