HDAC1 and cancer: Worth noting is also difluorobenzyloxy-substituted analogue 62 (Figure 29), described as a highly potent HDAC1 inhibitor (IC50 = 0.50 nM) with promising antiproliferative properties towards the MDA-MB-231, H157, and A549 cancer cell lines with IC50 values in the range of 1.95 μM to 7.58 μM [133].