SOD1 and colitis: A study conducted by Hajji et al. showed that GA collected from Northwest of Tunisia had a significant decrease in superoxide dismutase (SOD) and gluthation peroxidase (GPx) activities in the colon of AA-intoxicated animals compared to the controls, whereas GAAE (100, 200 and 400 mg/Kg, b.w.)or sulfasalazine (100 mg/Kg, b.w.)pretreatment over seven days significantly protected against this depletion when compared to the colitis group (p < 0.05) [10].