GLO1 and Anxiety: The mRNA expression of glyoxylase-1 (GLO-1) and GLO-1 protein expression were measured in 42 BALB/c mice submitted to stress using a conventional restraint model. The mRNA and protein expressions were found to be increased in animals given anxiety as compared to the normal control. Eugenol and its liposome-based nanocarriers counteracted this behavior, with liposomal eugenol behaving better than the compound alone.