Aim: demonstrate the hypothesis that antibiotic treatment with or without GnRHa may decrease intrauterine infection with consequent decrease in tissue inflammation, cell proliferation and angiogenesis in human endometriosisConclusion: Decreased Gardnerella, Prevotella, Acidibactor, Atopobium, Megasphaera, and Bradyrhizobium in patients with endometriosis in treatment with LVFX or LVFX + GnRHa, reduced occurrence rate of chronic endometritis after GnRHa + LVFX treatment comparison to GnRHa treatment group and decreased CD68, Ki-67, and CD31. Here, PECAM1 is linked to chronic endometritis.