ENO1 and central nervous system cancer: Moreover, an overexpression of the long noncoding RNA (lncRNA) small nucleolar RNA host gene 18 (SNHG18) in glioma resulted in the suppression of the translocation of ENO1 to the nucleus, promoting the motility of glioma cells and thus metastasis due in part at cytoplasmatic ENO1; in fact, the transgenic suppression of ENO1 inhibits the invasive capacity induced by the upregulation of SNHG18 in glioma cells [134].