ALDOC and glioblastoma: Aldo C overexpression decreases the invasive capacity of U87 GBM cells through TWIST1 transcriptional factor downregulation, which regulates the epithelial-mesenchymal transition through positive genic regulation of IL8, 1L1, 1L1β, matrix metalloproteinase 1 (MMP1), and fibronectin [94].