HSD17B10 and early-onset autosomal dominant Alzheimer disease: After 17β-HSD10 proved to be an important mitochondrial enzyme (see Figure 2 and Figure 4), people are asking whether mitochondria are dysfunctioning in Alzheimer’s disease [47,58,106] and how we could find a way to deal with progressive neurodegeneration [58,107,108,109,110].