PKC signaling pathways contribute to the key cellular responses central to asthma [283,284,285], chronic obstructive pulmonary disease (COPD) [286], idiopathic pulmonary fibrosis (IPF) [287], acute respiratory distress syndrome (ARDS) [288,289], and lung cancer [167,290], to mention a few. The gene discussed is PRRT2; the disease is idiopathic pulmonary fibrosis.