TLR4 and COVID-19: Additionally, RSV’s effects include inhibition of TLR4 (Toll-Like receptor 4) activation and inhibitions of proinflammatory transcription factor NF-κB and Th17 helper T-cells, which was promising in combating the COVID-19-mediated activation of TLR4 and the stimulation of proinflammatory cytokines (IL-1, IL-6, CCL-5 (chemotactic chemokine ligand 5)) and TNF-α [62,63].