Possible mechanisms of RSV are correlated with SIRT1 expression in that RSV, through SIRT1, stimulates PPAR gamma coactivator 1-alpha (PGC1α) activity [44] and, through AMPK, regulates several important processes including energy metabolism and mitochondrial functions (it is known that AMPK activity is dysregulated in hyperglycemia) [45]. This evidence concerns the gene SIRT1 and Hyperglycemia.