DUSP3 and melanoma: It is likely that a single cytokine or a combination of some cytokines secreted by LLC, but not by B16, may contribute to the recruitment of DUSP3−/− macrophages, which could explain the differential recruitment of macrophages to the site of LLC metastasis; as the article describes, they compared LLC-luciferase and B16-F10-luciferase melanoma cells administered to mice and saw that there was no difference for B16 in knockout of DUSP3 and its full manifestation, unlike LLC-luciferase.