It was suggested that PE increased the abundance of Akkermansia muciniphila, which was negatively correlated with the histological score of colitis in the intestinal tract of IL-10 knockout mice and decreased the abundance of Paeniclostridium and Clostridium_sensu_stricto_1, which were positively correlated with the histological score of colitis [35]. Here, IL10 is linked to colitis.