5-FU-miR-15a was also shown to significantly inhibit the expression of Yap1, Bcl2, Il6, and Mmp9, both alone and during treatment with TGFβ1 in murine and human Pancreatic Stellate Cells, suggesting the reduced proliferation and migration of pancreatic stellate and cancer cells [171]. This evidence concerns the gene TGFB1 and cancer.