The similarity of KRAS mutation rates across races may suggest that the chromosomal instability (CIN) pathway occurs at similar rates across races, whereas the difference in BRAF mutation rates between races may suggest that the sporadic MSI pathway and the CpG Island Methylator Phenotype (CIMP) pathway occur more frequently in Caucasians and less frequently in Middle Easterners. This evidence concerns the gene KRAS and cervical squamous intraepithelial neoplasia.