CLPX and Perrault syndrome: Among the disease proteins responsible for Perrault syndrome, HARS2 was prominent because of its strong accumulation in CLPP-null tissue, as previously reported upon quantitative immunoblots [17], and here, the complexomics profile revealed a parallel distribution of CLPX and HARS2 from their monomeric sizes (precursors of 69 and 23 kDa, respectively) up to molecular sizes around 250 kDa.