Consistent with the increased expressions of genes involved in neutrophil migration and chemotaxis in the lungs of SAA-TKO mice compared to WT mice in sepsis, there was a significantly increased number of neutrophils (13 ± 2.08 in SAA-TKO mice vs. 4.25 ± 0.25 in WT mice; Figure 6A) associated with significantly increased myeloperoxidase activity (59.51 ± 7.6 mU/mg in SAA-TKO vs. 26.26 ± 3.42 mU/mg in WT; Figure 6B) in the lungs of SAA-TKO mice compared to WT mice in CS-induced sepsis. This evidence concerns the gene SAA2 and Sepsis.