PARP1 and neoplasm: miR-125b-5p acts mainly as a tumour suppressor in many different ways, for example, interacting with VEGF (vascular endothelial factor), PARP 1 (poly-ADP-ribose-polymerase 1) and PRXL2A (peroxiredoxin like 2A gene, responsible for anti-oxidative processes) [47].