These genes are relevant to multiple PCa signaling pathways, including differentially Methylated Promoters (APC, GPX3), upregulated in PCa (ETV1), Androgen Receptor Signaling (AR, IL-6, FOXO1), AKT & PI3 Kinase Signaling (AR, IL-6, FOXO1), PTEN Signaling (IL-6), Apoptosis (ETV1, IL-6), Cell Cycle (APC), and Transcription Factors (AR, ETV1, FOXO1) (Table 2). Here, IL6 is linked to posterior cortical atrophy.