APOB and Lipedema: Felmerer et al. [9] demonstrated slight differences in the systemic lipid metabolism in lipedema, with systemic lipid values ranging between the upper physiological range and the slight pathological range (increased levels of total cholesterol: 1.31-fold; LDL: 1.46-fold; and TGs: 1.49-fold, with a 1.37-fold increase in apolipoprotein B compared with age- and sex-specific standardized physiological ranges).