Furthermore, Midostaurin, inhibiting FLT3 mutations (being present in 30% of newly diagnosed adults) [21], Venetoclax, inhibiting the anti-apoptotic protein BCL2 [22], and Ivosidenib or Enasidenib, inhibiting IDH1 or IDH2 mutations (being present in 7–19% of AML patients) [3], have become crucial components in AML therapy. The gene discussed is BCL2; the disease is acute myeloid leukemia.