Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis showed that the signaling pathways involved in the regulation of periodontitis by Asarum–Angelica were mainly the AGE–RAGE signaling pathway, NF-κB signaling pathway, JAK/STAT signaling pathway, small cell lung signaling pathway, etc. (see Figure 2D). This evidence concerns the gene SOAT1 and periodontitis.