The plasma NfL level was statistically higher (mean 23.1 [SD = 22.7]) in AD and differed between groups (Table 1) especially between AD dementia and naMCI participants (p < 0.001, Figure 1 and Table 1) and between aMCI and naMCI (p = 0.046, Figure 1). The gene discussed is NEFL; the disease is Alzheimer disease.