This resource revealed the single-cell gene expression profile of PAICS in human tongue tissue, highlighting its notable presence in epithelial cells and keratinocytes, as illustrated in Figure 2H. Additionally, we assessed the mRNA expression levels of DYRK3, PAICS, and PPAT in clinical samples from the TCGA HNSC cohort, which is detailed in Figure 2I. This analysis offers crucial data about the expression of these genes in oral squamous cell carcinoma (OSCC). Here, PAICS is linked to oral cavity squamous cell carcinoma.