LTB4R and cancer: To date, no useful assays are available for the assessment of leukotriene B4 receptor methylation status, and most of the studies use either the MDA-MB-231 cell line (TNBC with high LTB4R gene methylation) [53] or pan-cancer pure bioinformatic analysis of LTB4R expression data from microarray or RNA-seq experiments [33].