Recently, Li et al. conducted a thorough study on the mechanism of IL-1β-dependent EMT stimulation: they demonstrated a gradual change in the EMT-associated phenotype of A549 cells during long-term exposure to IL-1β, resulting in the retention of mesenchymal characteristics of tumor cells after removal of the inflammatory stimulus (a phenomenon called “EMT memory”) [62]. This evidence concerns the gene IL1B and neoplasm.