MTOR and breast adenocarcinoma: Khanfar et al. [41] documented that oleocanthal was able to inhibit the mTOR (mammalian target of rapamycin) signaling pathway in the breast adenocarcinoma cell line MCF-7 and in the human ductal breast epithelial tumor cell line T47D, with an IC50 value of 28.0 μM and 20.0 μM, respectively.