STAT3 and cancer: Oleocanthal has been shown to exert promising anticancer actions on different cancer cell lines through a multitude of mechanisms, such as the modulation of signaling pathways like the apoptotic pathway, the HGF (Hepatocyte growth factor)/c-Met (Mesenchymal-epithelial transition factor) pathway, and the signal transducer and activator of transcription 3 (STAT3) pathway, among others [10].