AKT1 and infection: Infected cell pathways are hijacked by an array of intracellular signaling cascades, such as the phosphatidylinositol 4,5-bisphosphate (PI3K)/AKT pathway, which underlies the clinical manifestation of different stages of infection by viruses such as the Epstein–Barr virus, hepatitis B and C viruses, human immunodeficiency virus (HIV), and influenza virus [6].