TLE3 and alkaline phosphatase measurement: In a study performed using a cerulein-induced murine model of AP to investigate the effect of GRg3, cerulein increased serum amylase, TNFα, IL-6, IL-1β, ROS, and Fe2+ levels, and GRg3 co-treatment decreased cerulein-induced ROS buildup and cell death in pancreatic tissues [78].