MECP2 and obstructive sleep apnea syndrome: For the epigenetic regulator genes, significantly different levels of expression were observed only at the trochophore stage for the DNA methylation machinery genes DNMT3b and MeCP2 and for the histone modifiers JmjCA, KDM2 and OSA, with a higher expression for DNMT3b and a lower expression for MeCP2, JmjCA, KDM2 and OSA in the treatment group than in the control group (p < 0.05; Figure 2).