Using adeno-associated virus (AAV)-Thyroxine binding globulin (TBG)-Cre or Foxl1-Cre mice to label hepatocytes or stem/progenitor cells, respectively, and two models of chemical hepatocarcinogenesis (induced by DEN/CCl4 or DEN/TCPOBOP (1,4-Bis[2-(3,5-Dichloropyridyloxyl)] benzene), the authors also demonstrated that tumor formation was driven by transformed hepatocytes [133]. Here, SERPINA7 is linked to neoplasm.