RPS14 and Bone marrow hypocellularity: As a consequence, cellular stress is caused by the deletion of RPS14, a gene that is frequently deleted alongside HSPA9 on deletion (5q) as a result of ribosomal insufficiency and P53 activation [31], and haploinsufficiency of deletion genes, such as RPS14 and HSPA9, may play a role in bone marrow failure and inadequate hematopoiesis in hematopoietic cells by activating wild-type TP53 and inducing apoptosis [70].